InfrafrontierGR offers a series of state-of-the-art mouse phenotyping services for the analysis of genotype-to-phenotype relationships, where proprietary disease models act as filters for “disease-oriented” characterization of mutations (secondary to tertiary phenotyping). These efforts aim at maximizing novel target identification and validation within the drug discovery pipeline, thus enhancing research and innovation potential. So far efforts focus on modeling chronic inflammatory diseases such as arthritis, multiple sclerosis, inflammatory bowel diseases, pulmonary fibrosis, modeled infections, as well as oncogene or inflammation-driven cancers, areas in which network members demonstrate research excellence and specialization. However additional phenotyping pipelines will be added shortly, covering areas of interest to regional researchers, including neurological/cognitive, cardiovascular and metabolic phenotyping pipelines.
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